Scholastic's The Magic School Bus: Space Exploration Game (1995) was the only game created on a medium other (Sega Genesis) than PC CD-ROM.
The premise was for the Magic School Bus to select a destination (starting with The Moon and reaching all the way out to Pluto). The game would then follow the same format; Ms. Frizzle would take off into outer space, and the player (sd Phoebe) would have to find her. All missions consisted of flying to the planet (while taking photographs of various space objects, shooting apart meteors, and collecting "space buoys" for fuel), landing the bus on a platform successfully, traversing the planet on foot to find Ms. Frizzle, and putting together a sliding jigsaw puzzle to complete the stage.
Enter = START
← → ↑ ↓ = LEFT / RIGHT / UP / DOWN
Q W E = X / Y / Z
A S D = A / B / C
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